Causes Of Cleft Lip And Palate Pdf

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A clinical examination followed by necessary diagnostic work-up was completed for each case. Environmental causes were found in 6 children four mothers developed hyperthermia during the 2 nd month of gestation, one mother was diabetic, and one mother was a known case of epilepsy and took sodium valproate throughout her pregnancy. Six children were suffering from known genetic malformation syndromes each with Jarcho-Levin syndrome, Oral-Facial-Digital syndrome type XI, Oral-Duplication syndrome, Kabuki syndrome, Fronto-nasal dysplasia and Nager syndrome.

They occur in approximately one in births. This causes a gap or defect to occur in the affected area, involving skin, muscle and the lining of the mouth. There is often an associated deformity of the nose on the affected side.

Cleft Lip and Palate

Cleft lip or palate is one of the most common types of craniomaxillofacial birth anomalies. Midface deficiency is a common feature of cleft lip and palate patients due to scar tissue of the lip and palate closure. Cleft lip and palate patients should be carefully evaluated by the craniofacial team in order to detect potentially serious deformities. Craniofacial team is involved with diagnosis of facial morphology, feeding problems, guidance of the growth and development of the face, occlusion, dentition, hearing and speech problems, and psychosocial issues and jaw discrepancy of the patients with cleft lip and palate or craniofacial syndromes. Treatment for cleft children requires a multidisciplinary approach including facial surgery in the first months of life, preventive and interceptive treatment in primary dentition, speech therapy, orthodontics in the mixed dentition phase, oromaxillofacial surgery, and implant and prosthetics in adults. Treatment plan from orthodontic perspective can be divided into the following stages based on the dentition stages: 1 presurgical orthopedics, 2 primary dentition, 3 mixed dentition, and 4 permanent dentition.

Cleft lip and cleft palate are birth defects that occur when a baby's lip or mouth do not form properly. They happen early during pregnancy. A baby can have a cleft lip, a cleft palate, or both. A cleft lip happens if the tissue that makes up the lip does not join completely before birth. This causes an opening in the upper lip. The opening can be a small slit or a large opening that goes through the lip into the nose. It can be on one or both sides of the lip or, rarely, in the middle of the lip.

Click here to view a larger image. The lip forms between the fourth and seventh weeks of pregnancy. As a baby develops during pregnancy, body tissue and special cells from each side of the head grow toward the center of the face and join together to make the face. This joining of tissue forms the facial features, like the lips and mouth. A cleft lip happens if the tissue that makes up the lip does not join completely before birth. This results in an opening in the upper lip. The opening in the lip can be a small slit or it can be a large opening that goes through the lip into the nose.

Related Conditions & Syndromes

Isolated cleft palate CPO is the rarest form of oral clefting. The incidence of CPO varies substantially by geography from 1. Approximately fifty percent of cases born with cleft palate occur as part of a known genetic syndrome or with another malformation e. The etiology of CPO is multifactorial involving genetic and environmental risk factors. In terms of environmental exposures, only maternal tobacco smoke has been found to be strongly associated with CPO. Some studies have suggested that maternal glucocorticoid exposure may also be important.

Facts about Cleft Lip and Cleft Palate

This means the cleft itself is caused by the condition or syndrome. When figuring out how likely a person with one of these is to pass on their cleft, you have to look at how likely they are to pass on the condition or syndrome first. Having a cleft alone does not mean that an individual has one of these conditions.

Cleft Lip and Palate

Clefts may affect one side unilateral or both sides bilateral of the lip. In nearly all cases, clefts of the lip affect the tip of the nose as well. Cleft lip and cleft palate can occur together or separately.

A cleft lip is an opening or split in the upper lip that occurs when developing facial structures in an unborn baby don't close completely. Cleft lip may be unilateral or bilateral. A baby with a cleft lip may also experience a cleft in the roof of the mouth cleft palate. A cleft palate is an opening or split in the roof of the mouth that occurs when the tissue doesn't fuse together during development in the womb.

Last Updated September This article was created by familydoctor. The word cleft means split or break. Cleft lip is an opening in the upper lip and nose. Cleft palate is an opening in the roof of the mouth palate. Babies can have a cleft lip, cleft palate, or both. A cleft may affect one side of the lip or palate, or both sides.

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Cleft Lip and Cleft Palate

 Чем могу помочь? - спросила она на гортанном английском.

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